| 2021-01-15 19:30:3215th January 2021 | Afan Lido  | 19:30:327:30 pm |  Carmarthen Town | JD Cymru (South) | N/A |
| 2021-01-23 14:30:3323rd January 2021 | Pontypridd Town  | 14:30:332:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2021-01-30 14:30:3830th January 2021 | Afan Lido | 14:30:382:30 pm |  Swansea University | JD Cymru (South) | N/A |
| 2021-02-05 19:30:135th February 2021 | Llanelli Town  | 19:30:137:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2021-02-13 14:30:5013th February 2021 | Afan Lido | 14:30:502:30 pm |  Port Talbot Town | JD Cymru (South) | N/A |
| 2021-02-27 14:00:0927th February 2021 | Trefelin  | 14:00:092:00 pm | Afan Lido | JD Cymru (South) | N/A |
| 2021-03-06 14:30:496th March 2021 | Afan Lido | 14:30:492:30 pm |  Cambrian & Clydach | JD Cymru (South) | N/A |
| 2021-03-20 14:00:1420th March 2021 | Undy Athletic  | 14:00:142:00 pm | Afan Lido | JD Cymru (South) | N/A |
| 2021-04-02 14:30:262nd April 2021 | Afan Lido | 14:30:262:30 pm |  Cwmbran Celtic | JD Cymru (South) | N/A |
| 2021-04-06 19:30:446th April 2021 | Goytre United  | 19:30:447:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2021-04-10 14:30:5410th April 2021 | Afan Lido | 14:30:542:30 pm |  Llantwit Major | JD Cymru (South) | N/A |
| 2021-04-23 19:30:3923rd April 2021 | Afan Lido | 19:30:397:30 pm |  Taffs Well | JD Cymru (South) | N/A |
| 2021-05-03 14:30:023rd May 2021 | Risca United  | 14:30:022:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2021-05-18 19:30:2418th May 2021 | Afan Lido | 19:30:247:30 pm |  Ammanford | JD Cymru (South) | N/A |
| 2021-05-22 14:30:3122nd May 2021 | Briton Ferry Llansawel  | 14:30:312:30 pm | Afan Lido | JD Cymru (South) | N/A |
