| 2021-07-17 14:30:1717th July 2021 | Cwmbran Celtic  | 3 - 0 |  Afan Lido | Cup | N/A |
| 2021-07-24 14:30:3524th July 2021 | Risca United  | 2 - 3 | Afan Lido | JD Cymru (South) | N/A |
| 2021-07-27 19:30:0727th July 2021 | Afan Lido | 0 - 3 |  Swansea University | JD Cymru (South) | N/A |
| 2021-07-30 19:30:4130th July 2021 | Afan Lido | 19:30:417:30 pm |  Llanelli Town | JD Cymru (South) | N/A |
| 2021-07-31 14:30:2631st July 2021 | Garden Village  | 14:30:262:30 pm | Afan Lido | Cymru Reserve League South West | N/A |
| 2021-08-01 14:00:111st August 2021 | Afan Lido Ladies  | 14:00:112:00 pm |  Cardiff Wanderers | South & West Women's League | N/A |
| 2021-08-07 14:30:127th August 2021 | Afan Lido | 14:30:122:30 pm |  Ynysygerwn | Cymru Reserve League South West | N/A |
| 2021-08-08 15:00:048th August 2021 | Llanelli Town | 15:00:043:00 pm | Afan Lido Ladies | South & West Women's League | N/A |
| 2021-08-10 19:30:5210th August 2021 | Afan Lido | 19:30:527:30 pm |  Undy Athletic | JD Cymru (South) | N/A |
| 2021-08-14 14:00:3614th August 2021 | Port Talbot Town  | 14:00:362:00 pm | Afan Lido | Cup | N/A |
| 2021-08-14 14:30:0414th August 2021 | Briton Ferry Llansawel  | 14:30:042:30 pm | Afan Lido | Cymru Reserve League South West | N/A |
| 2021-08-15 14:00:5115th August 2021 | Afan Lido Ladies | 14:00:512:00 pm |  Bridgend Street | South & West Women's League | N/A |
| 2021-08-20 19:30:4520th August 2021 | Taffs Well  | 19:30:457:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2021-08-22 14:00:2822nd August 2021 | Coed Duon  | 14:00:282:00 pm | Afan Lido Ladies | South & West Women's League | N/A |
| 2021-08-24 19:30:0824th August 2021 | Afan Lido | 19:30:087:30 pm |  Ammanford | JD Cymru (South) | N/A |
| 2021-08-27 19:30:2827th August 2021 | Afan Lido | 19:30:287:30 pm | Briton Ferry Llansawel | JD Cymru (South) | N/A |
| 2021-08-28 14:30:2028th August 2021 | Afan Lido | 14:30:202:30 pm |  Cwmamman United | Cymru Reserve League South West | N/A |
| 2021-08-29 14:00:3829th August 2021 | Afan Lido Ladies | 14:00:382:00 pm | Cwmbran Celtic | South & West Women's League | N/A |
| 2021-09-04 14:30:014th September 2021 | Carmarthen Town  | 14:30:012:30 pm | Afan Lido | Cymru Reserve League South West | N/A |
| 2021-09-05 14:00:405th September 2021 | Penybont  | 14:00:402:00 pm | Afan Lido Ladies | South & West Women's League | N/A |
| 2021-09-10 19:30:5810th September 2021 | Cambrian & Clydach  | 19:30:587:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2021-09-11 14:30:1911th September 2021 | Afan Lido | 14:30:192:30 pm | Port Talbot Town | Cymru Reserve League South West | N/A |
| 2021-09-17 19:30:2617th September 2021 | Afan Lido | 19:30:267:30 pm |  Goytre United | JD Cymru (South) | N/A |
| 2021-09-19 14:00:4819th September 2021 | Afan Lido Ladies | 14:00:482:00 pm |  Ystradgynlais Ladies | Women's Cup | N/A |
| 2021-09-26 14:00:2726th September 2021 | Afan Lido Ladies | 14:00:272:00 pm |  Tonyrefail | South & West Women's League | N/A |
| 2021-10-01 19:30:441st October 2021 | Ammanford | 19:30:447:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2021-10-09 14:30:139th October 2021 | Llantwit Major  | 14:30:132:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2021-10-22 19:30:5722nd October 2021 | Afan Lido | 19:30:577:30 pm | Cwmbran Celtic | JD Cymru (South) | N/A |
| 2021-10-24 14:00:2724th October 2021 | Pontardawe Town  | 14:00:272:00 pm | Afan Lido Ladies | South & West Women's League | N/A |
| 2021-10-30 14:30:2230th October 2021 | Afan Lido | 14:30:222:30 pm | Carmarthen Town | JD Cymru (South) | N/A |
| 2021-11-06 14:00:556th November 2021 | Trefelin  | 14:00:552:00 pm | Afan Lido | JD Cymru (South) | N/A |
| 2021-11-07 14:00:017th November 2021 | Afan Lido Ladies | 14:00:012:00 pm |  Aberaman | South & West Women's League | N/A |
| 2021-11-14 14:00:2914th November 2021 | Baglan Dragons  | 14:00:292:00 pm | Afan Lido Ladies | South & West Women's League | N/A |
| 2021-11-19 19:30:1819th November 2021 | Afan Lido | 19:30:187:30 pm |  Pontypridd Town | JD Cymru (South) | N/A |
| 2021-11-28 14:00:5528th November 2021 | Afan Lido Ladies | 14:00:552:00 pm |  Caerphilly Castle | South & West Women's League | N/A |
| 2021-12-03 19:45:353rd December 2021 | Pontypridd Town | 19:45:357:45 pm | Afan Lido | JD Cymru (South) | N/A |
| 2021-12-05 14:00:235th December 2021 | Newport City  | 14:00:232:00 pm | Afan Lido Ladies | South & West Women's League | N/A |
| 2021-12-10 19:30:2410th December 2021 | Afan Lido | 19:30:247:30 pm | Trefelin | JD Cymru (South) | N/A |
| 2021-12-17 19:30:3117th December 2021 | Carmarthen Town | 19:30:317:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2021-12-27 18:00:5827th December 2021 | Afan Lido | 18:00:586:00 pm | Port Talbot Town | JD Cymru (South) | N/A |
| 2022-01-01 14:30:311st January 2022 | Port Talbot Town | 14:30:312:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2022-01-09 14:00:039th January 2022 | Cardiff Wanderers | 14:00:032:00 pm | Afan Lido Ladies | South & West Women's League | N/A |
| 2022-01-21 19:30:3921st January 2022 | Goytre United | 19:30:397:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2022-01-23 14:00:3123rd January 2022 | Afan Lido Ladies | 14:00:312:00 pm | Llanelli Town | South & West Women's League | N/A |
| 2022-01-28 19:30:1928th January 2022 | Afan Lido | 19:30:197:30 pm | Cambrian & Clydach | JD Cymru (South) | N/A |
| 2022-01-30 14:00:5330th January 2022 | Bridgend Street | 14:00:532:00 pm | Afan Lido Ladies | South & West Women's League | N/A |
| 2022-02-06 14:00:146th February 2022 | Afan Lido Ladies | 14:00:142:00 pm | Coed Duon | South & West Women's League | N/A |
| 2022-02-12 14:00:5312th February 2022 | Cwmbran Celtic | 14:00:532:00 pm | Afan Lido | JD Cymru (South) | N/A |
| 2022-02-13 14:00:4113th February 2022 | Cwmbran Celtic | 14:00:412:00 pm | Afan Lido Ladies | South & West Women's League | N/A |
| 2022-02-20 14:00:5620th February 2022 | Afan Lido Ladies | 14:00:562:00 pm | Penybont | South & West Women's League | N/A |
| 2022-02-25 19:30:4825th February 2022 | Briton Ferry Llansawel | 19:30:487:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2022-03-04 19:30:174th March 2022 | Swansea University | 19:30:177:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2022-03-11 19:30:4911th March 2022 | Afan Lido | 19:30:497:30 pm | Llantwit Major | JD Cymru (South) | N/A |
| 2022-03-19 14:00:2319th March 2022 | Undy Athletic | 14:00:232:00 pm | Afan Lido | JD Cymru (South) | N/A |
| 2022-03-20 14:00:2420th March 2022 | Tonyrefail | 14:00:242:00 pm | Afan Lido Ladies | South & West Women's League | N/A |
| 2022-03-27 14:00:0027th March 2022 | Afan Lido Ladies | 14:00:002:00 pm | Pontardawe Town | South & West Women's League | N/A |
| 2022-04-01 19:30:341st April 2022 | Afan Lido | 19:30:347:30 pm | Taffs Well | JD Cymru (South) | N/A |
| 2022-04-08 19:30:428th April 2022 | Llanelli Town | 19:30:427:30 pm | Afan Lido | JD Cymru (South) | N/A |
| 2022-04-17 14:00:4317th April 2022 | Aberaman | 14:00:432:00 pm | Afan Lido Ladies | South & West Women's League | N/A |
| 2022-04-23 14:30:5123rd April 2022 | Afan Lido | 14:30:512:30 pm | Risca United | JD Cymru (South) | N/A |
| 2022-04-24 14:00:4524th April 2022 | Afan Lido Ladies | 14:00:452:00 pm | Baglan Dragons | South & West Women's League | N/A |
| 2022-05-01 14:00:041st May 2022 | Caerphilly Castle | 14:00:042:00 pm | Afan Lido Ladies | South & West Women's League | N/A |
